Pyridines and derivatives

Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.

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7,006 – 7,020 of 178,220 results

7,006

Medchemexpress LLC 2-(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorophenyl)pyrimidin-4-amine | 130800-90-7 | 99.6% | 372.68 | C15H16Cl3N5 | 1 ML

Sipatrigine is a neuroprotective small molecule that inhibits glutamate release and blocks voltage-dependent sodium and calcium channels. Supplied as a ready-to-use 10 mM solution in DMSO, this reagent is intended for research applications such as in vitro pharmacology and electrophysiology studies.

Ready-to-use 10 mM solution in DMSO.
Convenient 1 mL volume for small-scale experiments.
High purity (99.6%) suitable for research use.
Molecular weight 372.68; CAS 130800-90-7.
Reported activity as sodium and calcium channel inhibitor and glutamate release inhibitor.

Pricing & Availability

7,007

Medchemexpress LLC Berubicin (RTA 744 free base) | 677017-23-1 | 87.8% | 633.64 | 5 MG

Berubicin is a doxorubicin analog that can cross the blood-brain barrier. It inhibits P-gp and MRP1-mediated efflux and suppresses glioblastoma multiforme (GBM). This compound exerts toxic effects on leukemia cells by activating nuclear factor κB (NF-κB) and induces apoptosis in neuroblastoma cells, making it suitable for studies related to nervous system tumors.

Inhibits P-gp and MRP1-mediated efflux.
Suppresses glioblastoma multiforme (GBM).
Activates nuclear factor κB (NF-κB) and induces apoptosis in leukemia and neuroblastoma cells.
More effective than doxorubicin in inhibiting SH-SY5Y cell growth.
Prolongs the survival time of intracranial orthotopic glioma models in mice.

Pricing & Availability

7,008

Medchemexpress LLC Cedarwood terpenes | 68608-32-2 | MFCD00676669 | 97.0% | 50mg

Cedarwood terpenes is a natural terpene mixture that can be extracted from cedar wood[1]

Pricing & Availability

7,009

Medchemexpress LLC Pipequaline | 77472-98-1 | MFCD00866983 | 99.9% | 316.44 g/mol | C22H24N2 | 100 MG

Pipequaline (PK-8165) is a research chemical characterized as a partial benzodiazepine receptor agonist with anxiolytic activity. It is intended for preclinical investigations of GABAA/benzodiazepine receptor modulation and related neuropharmacology. Supplied as a high-purity solid for laboratory use; not for human or veterinary administration.

Partial benzodiazepine receptor agonist with anxiolytic activity.
Suitable for preclinical pharmacology and receptor binding studies.
High purity for reproducible experimental results.
Available in small milligram pack sizes to support dose-ranging work.
Molecular weight 316.44 g/mol, enabling stoichiometric calculations.

Pricing & Availability

7,010

Medchemexpress LLC 1-Azabicyclo[2.2.2]octan-3-one, 2,2-bis(hydroxymethyl)- | 5608-24-2 | 98.0% | 185.22 | 25 MG

PRIMA-1 is a mutant p53 reactivator that restores the sensitivity of TP53 mutant-type thyroid cancer cells to the histone methylation inhibitor 3-Deazaneplanocin A.

Reactivates mutant p53, restoring sensitivity in TP53 mutant-type thyroid cancer cells.
Significantly suppresses lung adenocarcinoma formation in mice.
Shows in vitro activity with IC50 values ranging from 35 to 75 μM in various cell lines.
Demonstrates in vivo activity, suppressing lung adenocarcinoma formation.

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7,011

Medchemexpress LLC Puliginurad (YL-90148) | 2013582-27-7 | 99.9% | 336.41 | 50 MG

Puliginurad (YL-90148) is a potent urate transporter (URAT) inhibitor. It can be used for hyperuricemia and gout research.

Shipping: room temperature in continental US; may vary elsewhere.
General storage: 4°C, sealed storage, away from moisture and light.
In solvent: -80°C for 6 months; -20°C for 1 month (sealed storage, away from moisture and light).

Pricing & Availability

7,012

Medchemexpress LLC 4-(4-acetyl-phenoxy)-butyric acid | 65623-82-7 | MFCD03658048 | 98.1% | 222.24 | C12H14O4 | 25 MG

AcBut (4-(4-acetyl-phenoxy)-butyric acid) is an acid-labile, cleavable ozogamicin linker used as a building block in antibody-drug conjugate (ADC) synthesis. It provides an acid-sensitive cleavage site for controlled payload release and is supplied as a high-purity solid suitable for conjugation chemistry.

Cleavable ozogamicin linker for ADC synthesis.
Acid-labile cleavage enables controlled payload release.
High purity suitable for conjugation chemistry.
Available in 25 mg, 50 mg, and 100 mg packages, larger sizes by quote.

Pricing & Availability

7,013

Medchemexpress LLC Fenoverine | 37561-27-6 | MFCD00865242 | 99.7% | 459.56 g·mol⁻¹ | C26H25N3O3S | 100 MG

Fenoverine is an antispasmodic research compound (CAS 37561-27-6) that modulates smooth muscle activity by inhibiting voltage-dependent calcium channels. It is provided as a high-purity analytical standard for preclinical pharmacology and analytical applications.

Antispasmodic compound for smooth muscle research.
Reduces calcium ion influx via voltage-dependent channel inhibition.
High purity: 99.7%.
Molecular formula C26H25N3O3S; molecular weight 459.56 g·mol⁻¹.
Available as solid powder and as a DMSO solution for biochemical assays.

Pricing & Availability

7,014

Medchemexpress LLC Benzamide, 2-chloro-N-[(S)-phenyl(2S)-2-piperidinylmethyl]-3-(trifluoromethyl)-, hydrochloride | 615571-23-8 | 99.4% | 433.29 g/mol | C20H21Cl2F3N2O | 5 MG

SSR504734 is a selective, reversible glycine transporter 1 (GlyT1) inhibitor supplied as the hydrochloride salt for research use (CAS 615571-23-8). It shows low-nanomolar potency across human, rat, and mouse GlyT1 and is orally active in preclinical models investigating cognition, anxiety, and depression. The compound is provided as a solid for laboratory studies and should be handled and stored according to standard research-chemical precautions.

High purity: 99.4%.
Selective, reversible GlyT1 inhibition with low-nanomolar potency.
Orally active in animal efficacy models.
White to off-white solid physical form.
Recommended storage: 4°C, protected from moisture and light.
For research use only; not for human or veterinary use.

Pricing & Availability

7,015

Medchemexpress LLC GSK1940029 (SCD inhibitor 1) | 1150701-66-8 | 99.8% | 391.25 | 50 MG

GSK1940029 (SCD inhibitor 1) | 1150701-66-8 | 99.8% | 391.25 | 50 MG

Pricing & Availability

7,016

Medchemexpress LLC 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-6-[(1S)-1-(3-phenoxy-1-azetidinyl)ethyl]-1-(tetrahydro-2H-pyran-4-yl)- | 99.9% | 25 MG

(S)-PF-04449613 is the left-handed isomer of PF-04449613, a selective PDE9A inhibitor. It exhibits an IC50 of 22 nM and has been observed to improve motor learning ability in a mouse model. This compound is provided as a white to light yellow solid.

Purity of 99.9%
Selective PDE9A inhibitor (IC50: 22 nM)
Improves motor learning ability in mouse models
Molecular weight of 395.45
Molecular formula: C21H25N5O3
Soluble in DMSO: 100 mg/mL
Stable for 3 years as powder at -20°C

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7,017

Medchemexpress LLC LIF Human HEK293 100ug

LIF protein induces terminal differentiation in leukemic cells promoting hematopoietic and neuronal cell differentiation and stimulating acute-phase protein synthesis in hepatocytes Its diverse activities highlight its role in influencing cellular differentiation across various cell types and physiological contexts LIF Protein Human (HEK293) is the recombinant human-derived LIF protein expressed by HEK293 with tag free

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7,018

Medchemexpress LLC Cipralisant (enantiomer) | 223420-11-9 | 100.0% | 216.32 g/mol | C14H20N2 | 1 ML

Cipralisant (enantiomer) is the enantiomeric form of cipralisant supplied as a 10 mM solution in DMSO for research use. It is intended for in vitro pharmacology and analytical applications related to histamine H3 receptor studies and is not for human or clinical use.

10 mM solution in DMSO for ready-to-use experiments.
1 mL sealed vial suitable for small-scale assays.
Molecular weight 216.32 g/mol for accurate calculations.
High enantiomeric excess (~96.4% ee) to support stereospecific studies.
Supplier-stated purity 100% for analytical consistency.
Characterization data available (COA, HNMR, NP-HPLC, LCMS) to support quality control.
Intended for in vitro H3 receptor pharmacology and analytical applications.

Pricing & Availability

7,019

Medchemexpress LLC Pamiparib | 1446261-44-4 | MFCD30489383 | 100.0% | 298.32 g·mol⁻¹ | C16H15FN4O | 25 MG

Pamiparib is an orally active, potent, and highly selective inhibitor of poly(ADP-ribose) polymerase (PARP) 1 and 2, commonly used as a research reagent in DNA damage response and oncology studies. It is provided as a high-purity solid suitable for in vitro assays and analytical applications.

Potent PARP1 and PARP2 inhibition (IC50 ≈ 0.9 nM and 0.5 nM).
High purity suitable for analytical use.
Available in small-scale packs for laboratory research.
Soluble in common organic solvents for stock solution preparation.
Supports studies of DNA repair, synthetic lethality, and antineoplastic mechanisms.

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7,020

Medchemexpress LLC σ1 receptor antagonist-1 | 1204401-49-9 | 99.9% | 337.48 | C21H23NOS | 1 ML

σ1 Receptor antagonist-1 is a selective sigma-1 receptor antagonist supplied as a 10 mM solution in DMSO for research use. The compound is identified by CAS 1204401-49-9, has molecular formula C21H23NOS, and a molecular weight of 337.48 g/mol. It is provided at high purity for in vitro pharmacology and biochemical studies; handle according to safety data sheet guidance.

Supplied as a ready-to-use 10 mM solution in DMSO.
High purity suitable for biochemical and cell-based assays.
Compact 1 mL volume convenient for multiple experiments.
Selective sigma-1 receptor antagonist activity for receptor pharmacology studies.
Structural identifiers provided for verification (SMILES, CAS).
Intended for research use only; not for human consumption.

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Pyridines and derivatives

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Medchemexpress LLC 2-(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorophenyl)pyrimidin-4-amine | 130800-90-7 | 99.6% | 372.68 | C15H16Cl3N5 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Berubicin (RTA 744 free base) | 677017-23-1 | 87.8% | 633.64 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cedarwood terpenes | 68608-32-2 | MFCD00676669 | 97.0% | 50mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pipequaline | 77472-98-1 | MFCD00866983 | 99.9% | 316.44 g/mol | C22H24N2 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1-Azabicyclo[2.2.2]octan-3-one, 2,2-bis(hydroxymethyl)- | 5608-24-2 | 98.0% | 185.22 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Puliginurad (YL-90148) | 2013582-27-7 | 99.9% | 336.41 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 4-(4-acetyl-phenoxy)-butyric acid | 65623-82-7 | MFCD03658048 | 98.1% | 222.24 | C12H14O4 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fenoverine | 37561-27-6 | MFCD00865242 | 99.7% | 459.56 g·mol⁻¹ | C26H25N3O3S | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Benzamide, 2-chloro-N-[(S)-phenyl(2S)-2-piperidinylmethyl]-3-(trifluoromethyl)-, hydrochloride | 615571-23-8 | 99.4% | 433.29 g/mol | C20H21Cl2F3N2O | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC GSK1940029 (SCD inhibitor 1) | 1150701-66-8 | 99.8% | 391.25 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-6-[(1S)-1-(3-phenoxy-1-azetidinyl)ethyl]-1-(tetrahydro-2H-pyran-4-yl)- | 99.9% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC LIF Human HEK293 100ug Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cipralisant (enantiomer) | 223420-11-9 | 100.0% | 216.32 g/mol | C14H20N2 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pamiparib | 1446261-44-4 | MFCD30489383 | 100.0% | 298.32 g·mol⁻¹ | C16H15FN4O | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC σ1 receptor antagonist-1 | 1204401-49-9 | 99.9% | 337.48 | C21H23NOS | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More